Pooping mucus only- VyWhy

Last updated on 2021-12-18 13:36:52


Usually, pooping mucus only is a result of severe inflammation or infection of the last part of the colon, rectum, or anal canal. Common causes include is dysentery, STDs of the anus and rectum,…

Usually, pooping mucus only is a result of severe inflammation or infection of the last part of the colon or the anorectal canal. Common causes include is dysentery, STDs of the anorectal canal, inflammatory bowel diseases, anorectal fissures, or inflamed hemorrhoids.

Common causes of pooping mucus only include:

  • Bacillary dysentery: is more likely to cause mucus only poops than other causes of dysentery
  • Sexually-transmitted diseases of the Anorectal canal are also a common cause of mucus in stool.
  • Inflammatory bowel disease: Crohn’s and ulcerative colitis.
  • Inflammed anorectal fissure or hemorrhoids.
  • Irritable bowel syndrome.
  • Rectal ulcers.
  • anorectal abscess/fistulas.
  • Antibiotic-associated colitis.
  • Food intolerances.
  • Anorectal cancers.
  • Radiation colitis, proctitis.
  • Diversion colitis.
pooping mucus only

1- Bacillary dysentery.

Dysentery is the passage of blood, mucus, or both with stool. Dysentery is usually caused by infections of your colon (large intestine).

If the colon inflammation is severe or involves theirectum, it can lead to mucus only poop (mucus discharge).

Two main organisms can cause dysentery:

  • Shigella bacteria: causes bacillary dysentery.
  • Entamoeba Histolytica protozoan: causes amoebic dysentery.

Dysentery is the most common cause of pooping mucus, but Bacillary dysentery is more severe and more likely to cause mucus only poop. This is because Shigella commonly causes proctitis (rectal inflammation).

You can get infected by shigella via contaminated food (food poisoning) or touching contaminated surfaces. Shigella is highly contagious even and may cause outbreaks of dysentery especially in children.

Symptoms suggesting bacillary dysentery.

  • The onset is acute, if you have recurrent mucus poop, dysentery is unlikely.
  • Intense abdominal pain, especially in the lower abdomen.
  • Diarrhea is associated with mucus and blood.
  • In severe cases, mucus only stools. Mucus and blood can come out without feces.
  • Tenesmus: intense urgency to poop, but only mucus or a small amount of poop comes out.
  • Fever: usually high grade.
  • nausea or vomiting (rarely present with bacillary dysentery).

Bacillary dysentery symptoms can range from mild diarrhea to intense dysentery, blood or mucous stools, and high-grade fever.

Mild symptoms are usually self-limiting, but severe forms of the disease (such as mucus only poop) require you to seek medical help.

2- Amoebic dysentery.

Entamoeba Histolytica is a common protozoan that can cause dysentery with blood and mucus in stool.

Amoebic dysentery is usually milder than bacillary dysentery. It is less likely to cause mucus only poop, but it happens with severe forms of the disease.

Symptoms of amoebic dysentery are similar to bacilliary dysentery, the main differences are:

  • The onset is more gradual (usually over one to three weeks), the severity is less than bacillary dysentery.
  • can range from mild diarrhea to severe dysentery with mucus and blood in the stool.
  • abdominal pain and fever are milder.
  • Tenesmus is moderate.
  • The stool is usually more formed and bulky, blood and mucus are usually mixed with feces (with bacillary dysentery, blood and mucus come out without feces).
  • In severe cases, Entamoeba organisms can invade the wall of the colon and cause intestinal perforation and cause fulminant inflammation of the colon.

3- – Other infections and food poisoning (foodborne illnesses).

Some other infections (especially bacteria) can infect your colon andirectal canal and cause mucus only poop.

Some other causes of dysentery and mucus only poop (ref):

  • Salmonella (typhoid fever).
  • E. coli (Shiga toxin-producing, Entero-invasive E. coli).
  • Clostridium Difficile.
  • Cytomegalovirus colitis.
  • And other less common organisms.

The above organisms can cause dysentery with mucus and blood in the stool. symptoms may vary from mild to severe and persistent illness.

The acute onset and presence of intense abdominal pain and fever are suggestive of infectious diarrhea and dysentery.

4 – Sexually transmitted diseases (STDs) of the Anorectal canal.

Sexual activities involving the anorectal canal can lead to infections, inflammation, and ulcers. Not all STDs of the anorectal canal lead to mucus in stool.

Possible organisms that can cause tenesmus and mucus poop:

  • Ano-rectal Gonorrhea.
  • Chlamydia causes severe tenesmus, rectal ulcers, mucus, and blood in the stool. it is possible to have mucus only poop with chlamydia infection of the anorectum.
  • Syphilis causes painful ulcers and anorectal pain and discharge (which can be mucus).
  • Sexually transmitted campylobacter Jejuni: causes ulceration of the rectal mucosa, diarrhea (which can be bloody and mucous, cramps, bloating, mucus in stool.

When to suspect:

  • Recent anorectal sexual activities with an infected or carrier partner.
  • Your partner doesn’t need to have symptoms.
  • The most commonly reported sexually transmitted disease in the USA is Chlamydia. it can cause rectal ulcers or access. this presents with severe anorectal pain, mucus only poop, or pus discharge.
  • Fever may also present.

5 –  Anorectal Fissure

An analfissure is a breakdown in the lining of the analcanal. It leads to anorectal pain and severe irritation which can lead to mucus or pus discharge instead of poop.

Fissures commonly occur due to:

  • Chronic constipation.
  • Normal vaginal delivery in females.
  • Local trauma of theianus.
  • Chronic inflammatory diseases of theianus such as Crohn’s disease or anorectal Cancer.


  • Severe anorectal pain increases while your poop is the main symptom. Almost, there is no fissure without sharp pain.
  • History of the causes such as severe constipation or local trauma to theianus.
  • With chronic fissures, you may feel a skin tag at the opening of your anorectal canal.

What to expect:

  • Your doctor will confirm the fissure by performing a local exam of the anorectal canal.
  • Most acute fissures will resolve within a few weeks, but they may turn chronic.
  • Treatment can include oral medications, local creams, or even surgery in severe cases.
  • The most important step is to prevent the cause such as treating constipation and eating a high-fiber diet.

6 – Inflamed Hemorrhoids.

Hemorrhoids are dilated inflamed veins in the wall of the analcanal. Inflamed hemorrhoids can irritate the canal and secrete mucus.

Mucus from the inflamed hemorrhoids can come out without stool. It is associated with the urge to poop even after having a bowel movement (ref).

A bulge or a skin tag may be felt at the opening of theianus. Whether you are diagnosed with hemorrhoids before or not, you have to see your doctor if you’re pooping only mucus with the hemorrhoids.

7- Inflammatory Bowel Diseases (Crohn’s & Ulcerative Colitis).

Inflammatory Bowel Disease is a term to describe two conditions (Crohn’s disease and ulcerative colitis). A disease that is caused by chronic inflammation and ulcers in the digestive tract.

The cause of IBD is unknown, but it is thought to be a result of a defective immune system (an autoimmune disease) (ref).

Ulcerative colitis affects only the large intestine (usually the last part including the descending colon, sigmoid colon, and rectalcanal). Crohn’s disease affects any part of your digestive tract from the mouth to theanus.

Chronic inflammations and ulcers (especially in the last part of the colon and the rectalicanal) can lead to recurrent diarrhea, stool urgency, blood, or mucus in stool. bloody and mucous discharge is more common with Ulcerative colitis (ref).

Symptoms suggesting IBD:

  • Persistent diarrhea.
  • Abdominal pain.
  • Rectal bleeding/Bloody stool.
  • The severe urge to poop but only mucus or blood comes out (tenesmus).
  • Weight loss.
  • Fatigue.
  • Mucus in the stool.
  • Fever may occur.

Mucus-only poop can be a result of the affection of your rectalcanal with either Crohn’s or ulcerative colitis. Either inflammation or ulcers lead to increased mucus in the rectalcanal which can come out without poop.

The diagnosis of Inflammatory bowel disease usually requires colonoscopy. It is treated with medications that decrease inflammation and suppress immunity (such as corticosteroids) (ref).

8- Irritable bowel syndrome (especially the diarrhea-predominant form).

Irritable Bowel Syndrome is very common, up to 15% of all people suffer from manifestations of IBS (ref).

IBS is a common cause of mucus in stool. Although it is possible to poop only mucus with IBS, usually mucus comes with the stools.

IBS is an underdiagnosed condition, it is estimated that up to 70% of people with IBS criteria don’t seek a diagnosis.

symptoms suggesting IBS (ref):

  • Recurrent abdominal pain at least one day per week for the last 3 months.
  • The onset of pain is associated with stool frequency (diarrhea or constipation).
  • The abdominal pain is relieved (or increased) after defecation.
  • Change in stool form (loose or hard stools).
  • Mucus in stool, or rarely, mucus only stool.
  • Absence of other causes of the above symptoms.

Read this in-depth article about how is IBS diagnosed.

If you have symptoms consistent with IBS, seek medical advice. And remember, Mucus only stools are rare with IBS.

9- Anorectal abscess or perianal fistula.

The abscess is an infected sac of tissue in the wall of the anorectal canal filled with pus.

The fistula is a small channel that connects an infected anal gland (in the tissue near theianus) to an opening on the skin.

Both conditions can lead to the discharge of blood, pus, or mucus from with or without a stool. the conditions usually present with:

  • Swelling, severe pain, or tenderness of the perianal tissue.
  • Rectal discharge (blood, pus, or mucus only poop).
  • Constipation (as a result of fear of painful bowel movements).
  • Fever and fatigue may occur.
  • You may have an opening discharging pus or blood in the perianal area (Perianal Fistula).

10- RectaliUlcers.

Rectal ulcers are painful sores in the wall of your rectali canal. It can occur as a result of a variety of causes or due to a condition called solitary rectal ulcer syndrome (SRUS).

Common causes of rectali ulcers:

  • Inflammatory bowel diseases (Crohn’s and Ulcerative colitis).
  • Severe constipation.
  • Radiotherapy of the rectalcanal
  • Ulcerated rectal tumor.
  • Solitary Rectal Ulcer Syndrome (SRUS): a very rare disease.

Symptoms of rectal ulcers:

  • Blood or mucus discharge from theianus.
  • Rectal Pain.
  • Painful bowel movement.
  • Tenesmus: urge to poop but nothing comes out or only mucus or blood poop.

11- Antibiotic use.

Overuse of some antibiotics may cause an inflammation of the colon. Antibiotics can kill the beneficial micro-organisms inside your colon and small intestine.

As a result, you may acquire infection with harmful bacteria that cause severe inflammation of the colon and the rectalicanal.

For example, Clostridium Difficile infection of the colon after antibiotic use. This usually occurs in people with a weakened immune system, using a medicine that reduces stomach acid or having previous digestive system surgery.

Most antibiotics can cause such conditions, but strong antibiotics with broad antibacterial spectrum such as penicillins, Cefotraxone, or ciprofloxacin. Also, using more than one antibiotic at the same time will raise the risk.

A severe condition with the destruction of the colon lining due to inflammation is called “pseudomembranous colitis” that may result from faulty use of antibiotics (ref).

This condition usually presents with intense diarrhea, blood, and mucus in bowel movements, fever, and severe abdominal pain.

Contact your doctor if you experienced mucus only poop after taking an antibiotic.

12- Food Intolerance.

Many foods can induce inflammation of the colon and rectal lining as a result of the sensitivity of your body to these diets.

severe inflammation of the lining will usually result in diarrhea, mucus in stool, or mucus-only stools in severe cases.

Common examples of food intolerance.

  • Lactose intolerance (milk and other dairy products).
  • Fructose intolerance.
  • FODMAP intolerance (as in people with IBS).
  • Gluten intolerance (present in wheat and barley): results in severe diarrhea and malabsorption, severe disease is called “celiac disease”. Also, some people may have Non-celiac gluten sensitivity (milder form).

Read more about food intolerance here.


13- Less Common.

A- Colorectal Cancer.

a mass in the last part of the colon or the rectalcanal may cause inflammation or ulceration. This can present with tenesmus, blood in the stool, or mucus discharge. Risk factors include being older than 40, having a family history of colorectal cancer, or weight loss.

colorectal cancer is one of the most common tumors. but its incidence as a cause of mucus only stools remains low compared to the causes mentioned above.

Always consult your doctor if you have risk factors. learn more here

B- Anorectal cancer.

Analicancer is a growth in the last part of the digestive tract. it usually presents with pain in the area of theianus, a sense of mass inside theianus.

  • A sense of incomplete evacuation of stool.
  • Bleeding peranus.
  • perianal itching.
  • Mucus in the stool.

Learn more HERE.

C- Intestinal Obstruction.

a bowel obstruction can be caused by a variety of conditions such as:

  • Impacted hard stools.
  • scar tissues.
  • herniasi
  • Tumors of the gut.
  • Swallowing of non-food items.
  • Twisting of the intestine.

Bowel obstruction presents with:

  • absolute constipation, No stool at all, only mucus poop can occur.
  • Abdominal distension and bloating.
  • severe abdominal pain.
  • Vomiting usually occurs, it can be persistent.

if you have absolute constipation, vomiting, severe abdominal distension, and mucus-only poops you have to seek medical help. The condition may require surgery to resolve.

Learn more at the Mayo clinic.


D- Radiation Therapy.

Radiation therapy for abdominal and pelvic tumors can result in severe inflammation of the anorectal canal. This can lead to mucus or blood in the stool. Consult your doctor if you experience mucus-only poop after radiotherapy.

E- Diversion Colitis.

Ostomy operations such as ileostomy or colostomy may lead to inflammation of the colon.

with ostomy operation, the stool leaves the body, not through the rectalicanal, but an artificial opening in your abdomen connected to a bag.

This leaves the rest of the colon and the anorectal canal empty from the stool. It is common to pass mucus only poop in patients with ostomy operations. either due to inflammation of the colon (diversion colitis) or due to mucus build-up inside the non-functioning colon.

learn more here.

F- Eosinophilic Proctititis / Allergic colitis.

Another cause of mucus-only poop is the allergic inflammation of the colon or the rectalicanal.

A condition called Eosinophilic proctocolitis is usually caused by milk or soy protein allergy. usually more common in children.

Inflammed mucosa of the colon and the rectalicanal leads to diarrhea, and mucus in stool.

This condition cal also presents later in the adolescent age (not restricted to early childhood). If the mucus only poop is associated with milk ingestion, seek medical help to diagnose the condition.

Learn more about this condition

When to see a doctor for mucus only poop.

Mild acute attacks of mucus only poop are usually due to dysentery. a single day with diarrhea and mucus can be self-limiting especially if you are not feverish or dehydrated.

See a doctor if:

  • severe attacks of mucus in stool, with an urgency that lasts for more than one day.
  • Fever.
  • Intense abdominal pain.
  • Recurrent vomiting.
  • Prolonged mucus in poop for more than one month without explained cause.
  • weight loss.
  • Blood in stool.
  • Signs of dehydration such as dizziness, extreme thirst, shortness of breath, rapid heartbeats, or confusion.


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28-04-2022 · The onset of abdominal pain is associated with diarrhea or loose stool (change in stool form). Gas and bloating are frequent in people with IBS. Intermittent or constant diarrhea. Mucus in the stool. The IBS is usually triggered by: Certain foods such as FODMAPs. Alcohol and caffeine. Fatty foods and spicy foods. Stress and anxiety. 5 ...


Chronic or recurrent loose stool every day or mild diarrhea is common. Most cases are due to food reactions and functional gut diseases.

The most common causes of constant loose tools every day are lactose intolerance, irritable bowel syndrome with diarrhea, FODMAP malabsorption, celiac disease, medications, and others.

The table below illustrates the common, infrequent, and rare causes of chronic loose stool or diarrhea (reference).


1- IBS-diarrhea
2- Bile acid diarrhea
3- Diet:– FODMAP malabsorption– Lactase deficiency– Artificial sweeteners (eg, sorbitol, xylol in chewing gum, soft drinks)– Caffeine (eg, coffee, coke, energy drinks)– Excess alcohol

– Excess liquorice

4- Colorectal cancer
5- Inflammatory bowel disease
6- Celiac disease
7- Drugs
8. Recurrent Clostridioides (formerly Clostridium) difficile diarrhea
Overflow diarrhea
– Small bowel bacterial overgrowth
– Mesenteric ischemia
– Lymphoma
– Surgical causes (eg, small bowel resections, fecal – incontinence, internal fistula)
– Chronic pancreatitis
– Radiation enteropathy
– Pancreatic carcinoma
– Hyperthyroidism
– Diabetes
– Giardiasis (and other chronic infections)
– Cystic fibrosis
– Other small bowel enteropathies (eg, Whipple’s disease, tropical sprue, amyloid, intestinal lymphangiectasia)
– Hypoparathyroidism
– Addison’s disease
– Hormone secreting tumors (VIPoma, gastrinoma, carcinoid)
– Autonomic neuropathy
– Factitious diarrhea
– Brainerd diarrhea (possible infectious cause not identified)

Today we will discuss the most common causes that may cause constant loos stool or diarrhea every day:

1 . FODMAP intolerance.

FODMAP refers to Fermentable oligo-, Di-, Monosaccharides, and polyols. They’re a broad group of foods with short-chain sugar.

Short-chain sugars are rapidly fermentable inside your intestine. As a result, the bacteria inside your gut use this carbohydrate as a source of diet. However, too many FODMAPs can cause constant loose stool every day.

FODMAP intolerance is very common among people with Irritable bowel syndrome. However, it can present with mild digestive symptoms such as abdominal discomfort and loose stool without the complete picture of IBS.

The table below shows the most common FODMAPs(reference):

  Sugar typeFoods containing
OOligosaccharidesFructans, galactooligosaccharidesWheat, barley, rye, onion, leek, the white part of spring onion, garlic, shallots, artichokes, beetroot, fennel, peas, chicory, pistachio, cashews, legumes, lentils, and chickpeas
DDisaccharidesLactoseMilk, custard, ice cream, and yogurt
MMonosaccharides“Free fructose”Apples, pears, mangoes, cherries, watermelon, asparagus, sugar snap peas, honey, high-fructose corn syrup
PPolyolsSorbitol, mannitol, maltitol, and xylitolApples, pears, apricots, cherries, nectarines, peaches, plums, watermelon, mushrooms, cauliflower, artificially sweetened chewing gum, and confectionery

Eating excess amounts of milk, fruits, and vegetables enlisted above causes symptoms such as:

  • Abdominal distension and discomfort after eating.
  • Bloating.
  • Diarrhea or loose stool.
  • People who continue to overeat FODMAPS often have constant loose stool or diarrhea.
  • The symptoms improve after defecation.
  • Severe cases may develop irritable bowel syndrome (see later).

Learn more.

2. Lactose intolerance.

Lactose is the chief sugar found in milk and dairy products. It is one of the FODMAP sugars.

Lactose intolerance is very common. As we grow, we begin to lose the ability to digest lactose properly due to a natural decline in the lactase enzyme inside our digestive system.

Some races have a 100% prevalence of lactose intolerance. Overall, the prevalence of lactose intolerance among adults is about 65%.

Lactose intolerance affects too many people, and most of them don’t know they have it. In addition, it may constantly cause loose stools in people who regularly drink milk or intake dairy products.

The symptoms of lactose intolerance include:

  • Loose stool or diarrhea: associated with ingestion of lactose in milk and dairy products.
  • Recurrent cramps.
  • Bloating and distension (very common due to rapid fermentation of lactose with the production of gas).
  • Flatulence (passing gas all the time).
  • Nausea (more prevalent when you intake excess amounts of lactose).
  • A sense of fullness and discomfort for several hours after eating dairy.
  • Vomiting can occur in severe cases.
  • Less commonly: Headache, muscle aches, joint pain, mouth ulcers, and impaired concentration (reference).

The symptoms of loose stool usually improve when you decrease or cut dairy from your diet. However, you don’t have to cut milk and dairy completely from your diet. Restricting the amount you intake may be enough to prevent loose stools.

Learn More about Lactose intolerance.

3 . Other forms of food intolerance and allergy.

Other less common forms of food intolerance that cause recurrent or constant loose stool include:

  • Caffeine intolerance: Excess caffeine intake daily may be responsible for constant loose stools. Caffeine stimulates the motility of your digestive tract, making your stool looser.
  • Excess alcohol intake (Alcohol intolerance).
  • Excess licorice.
  • Regular consumption of artificial sweeteners such as sorbitol, aspartame, xylitol, and mannitol.

4 . Irritable bowel syndrome.

IBS or irritable bowel syndrome is the most common functional gut disease. Alone, IBS represents 40% of the patients at gastroenterologist clinics and affects about 10 to 15% of people with IBS (reference).

Interestingly, some studies estimate that 60% of people with IBS symptoms don’t know they have the disease! (reference).

People with IBS are often sensitive to FODMAPs (discussed above). However, the main feature of IBS is recurrent abdominal pain or discomfort with bowel habit changes.

Constantly loose stool every day with recurrent abdominal pain for months is likely to be IBS until proven otherwise.

Symptoms (how to suspect IBS-diarrhea):

  • Abdominal pain: It is the cardinal feature of IBS. No IBS without abdominal pain. IBS patients get abdominal pain at least one day per week (for a minimum of three months).
  • The pain often improves after bowel movements. But it may become worse after defecation.
  • The onset of abdominal pain is associated with diarrhea or loose stool (change in stool form).
  • Gas and bloating are frequent in people with IBS.
  • Intermittent or constant diarrhea.
  • Mucus in the stool.

The IBS is usually triggered by:

  • Certain foods such as FODMAPs.
  • Alcohol and caffeine.
  • Fatty foods and spicy foods.
  • Stress and anxiety.

5 . Medications.

Many medications can alter your bowel habits and cause diarrhea or loose stool.

Unfortunately, they are often overlooked as a cause of diarrhea or loose stool.

If you constantly have loose stool, review your list of medications for any of the below drugs:


  • Metformin and gliptins (anti-diabetes medications).
  • Antibiotics: particularly penicillins cephalosporins.
  • Laxative overuse.
  • Stomach/GERD medications: especially Proton Pump Inhibitors such as Omeprazole (Prilosec), Esomeprazole (Nexium), and Pantoprazole (Protonix).
  • Antidepressants such as Citalopram (Celexa) and Escitalopram (Lexapro).
  • Chemotherapy.
  • Non-steroidal anti-inflammatory drugs: such as Ibuprofen (Advil).
  • Cholcicine (Colcrys, Mitigare).
  • Anti-hypertensive medications include Enalapril (Vasotec) and Lisinopril (Zestril, Prinivil).
  • More than 700 medications can cause diarrhea or loose stool: The complete list is HERE and HERE.

6. Celiac disease.

Celiac disease is a condition where your immune system attacks the lining of your digestive tract. It is a reaction to a protein called (gluten) found in wheat, rye, and barley.

The allergic reaction to these foods leads to severe inflammation and malabsorption of nutrients.

Patients with celiac disease often have constant diarrhea or loose stool every day as long as they eat gluten.


  • Age of onset: often between 20-30 years, but it can occur at any age (up to 70).
  • Recurrent abdominal pain.
  • Bloating.
  • Diarrhea or loose stool constantly every day.
  • Nausea and/or vomiting.
  • Weight loss.
  • Itching and skin rashes.
  • Easy fatigue, shortness of breath, dizziness, and headaches (due to anemia).
  • Bone aches (due to osteoporosis and osteomalacia).

7. Others.

  • Bile acid diarrhea.
  • Post-cholecystectomy syndrome.
  • Small intestinal bacterial overgrowth.
  • And others (see the table above).
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06-03-2022 · Bile acid diarrhea (BAD) is one of the most underrated causes of chronic diarrhea or loose stool. Usually, your small intestine reabsorbs more than 95% of bile excreted from the liver through the gallbladder and bile duct ( reference ). Excess bile …


Irritable bowel syndrome is a digestive system disease characterized by recurrent abdominal pain and bowel changes.

IBS is a functional disease. Functional means that the doctor couldn’t find anything wrong in the colon and stool by investigations.

It is one of the most common diseases. About 10-15% of people worldwide have IBS (reference).

IBS is a chronic abdominal pain and stool changes (diarrhea or constipation) syndrome.

Diarrhea-predominant IBS is a widespread reason why your poop is not solid anymore.

IBS is an under-diagnosed condition. Only 40% of people matching the diagnostic criteria of IBS seek medical advice (reference).

This leaves 60% of IBS sufferers unaware that they have such a condition.

Symptoms suggestive for IBS include:

  • Abdominal pain is often recurrent or constant (occurring at least one day per week for the past three months).
  • The pain is related to bowel movements (either improves or worsens with bowel movements).
  • The onset of pain is associated with either diarrhea or constipation.
  • Constant diarrhea can occur in the IBS-Diarrhea subtype.
  • Gas and bloating.
  • Mucus in the stool.
  • The symptoms of IBS are often triggered by certain foods and anxiety.
  • No signs of inflammation or infection such as fever, vomiting, or weight loss.

2. Lactose intolerance.

Lactose is a type of sugar mainly present in milk and other dairy products.

Lactose intolerance is the most common form of food intolerance. Studies show that around 25% of the white race has lactose intolerance (reference).

Shockingly, lactose intolerance may affect up to 90% of other races, such as blacks, Native Americans, and Asian Americans (reference).

If you are a regular consumer of milk or dairy products, lactose intolerance may be the reason why your stool is never solid anymore.

What causes lactose intolerance?

The lactose sugar needs an enzyme called (lactase) to be digested and absorbed. Lactose intolerance occurs when your small intestine cannot produce enough (lactase) (reference).

The lactase enzyme deficiency can be:

  • Primary lactase deficiency: is a hereditary disease leading to gradual loss of lactase enzyme function (most common cause).
  • Secondary lactase deficiency: due to injury to the intestinal mucosa as with gastroenteritis, celiac disease, IBD, chemotherapy, or antibiotic use.

Symptoms suggestive of lactose intolerance:

  • Loose stools or diarrhea.
  • Stomach pain.
  • Bloating and distension.
  • Passing too much gas (flatulence).
  • Nausea after eating dairy products.
  • Fullness and early satiety.
  • Vomiting can occur in severe cases.
  • Less commonly: Headache, muscle aches, joint pain, mouth ulcers, and impaired concentration (reference).

Lactose intolerance is a widespread condition. So, consider consulting your doctor if you consistently get so much gas all the time.

Also, you can run a small experiment by eliminating dairy for a week and notice the changes in gas amounts. Then, tell your doctor or nutritionist if cutting lactose improves your condition.

More: What happens if you ignore lactose intolerance?

3. Other types of food intolerance.

Food intolerance affects up to 20% of the population. This means one in every five persons will have some intolerance to one or more types.

Developing intolerance can be as soon as after birth or later in life at any age. For example, intolerance can be why your poop is not solid anymore.


  • Loose stool or diarrhea.
  • Bloating, excess gas, and flatulence.
  • Abdominal pain.
  • Nausea, and sometimes vomiting.
  • Heartburn.

Common types:

  • Lactose intolerance:Present in milk, ice cream, mustard, some types of cheese.
  • Fructose intolerance:Present in many fruits and honey.
  • FODMAPs intolerance:
    It affects people with IBS. FODMAPs refer to “Fermentable Oligo-, Di-, Monosaccharides, and Polyols. FODMAPs are a group of short-chain carbohydrates that cause gas and digestive disturbances. They are present in various foods, vegetables, fruits, and artificial sweeteners. Learn more.
  • Caffeine intolerance:
    Caffeine in coffee, teas, chocolates is one of the most common causes of constant diarrhea. In addition, caffeine is usually abused in large amounts, which raises the risk of diarrhea.
  • AIcohoI intolerance:
    Too much aIcohoI intake leads to loose stool or diarrhea, and some of them are high in FODMAPs and can trigger IBS symptoms.
  • Gluten intolerance:It causes Celiac disease (see later) and another milder form called “Non-celiac gluten sensitivity.”
  • Amines intolerance:
    Bacteria produce amines during food storage and fermentation.
  • Salicylates intolerance:
    Salicylates are naturally occurring chemicals. They present in a wide variety of foods, including fruits, vegetables, coffee, and teas.
  • Sulfite intolerance:
    Sulfite is used as a natural preservative for foods.
  • Food allergy:
    Some foods can cause more severe allergic reactions, such as Nuts, peanuts, raw meat, seafood, mustard, rice, and some fruits and vegetables.

4. Celiac diseases.

Celiac disease is a common condition affecting 1% of the world population.

With celiac disease, your body is intolerant to ” gluten ” protein” Gluten is found mainly in:

  • Wheat and wheat-based foods such as bread.
  • Rye.
  • Barley.

A small intestinal inflammation with malabsorption develops after eating gluten-containing foods. The poop of the person with celiac disease is often loose or watery. It is never solid anymore.

Symptoms suggesting celiac disease:

  • The usual age of onset is between 20-30 years of age. But it can occur in older generations up to 70 years.
  • Abdominal pain and bloating.
  • Constant diarrhea.
  • Diarrhea can also be intermittent or not present. Constipation can also occur.
  • Nausea and vomiting.
  • Weight loss.
  • Easy fatigue and iron deficiency anemia.
  • Itchy, blistery skin.
  • Osteoporosis and osteomalacia (body aches).

Celiac disease is diagnosed by a blood test or biopsy from the small intestine.

Call your doctor if you suspect celiac disease. Learn more.

5. Small intestinal bacterial overgrowth (SIBO).

Small intestinal bacterial overgrowth (SIBO) is an abnormal increase in the overall bacteria inside your small intestine.

SIBO results from certain diseases such as Crohn’s disease, diabetes, antibiotic use, or specific surgeries.

SIBO leads to a complex of symptoms as:

  • Abdominal pain.
  • Bloating and too much gas all the time.
  • Diarrhea or loose stool. 
  • Nausea or vomiting.
  • Loss of appetite.
  • Weight loss, malnutrition.

SIBO is widely recognized nowadays due to advancements in its diagnosis. However, SIBO is still underdiagnosed in many countries.

Also, SIBO is linked to many other digestive diseases, such as IBS. So talk. So talk with your doctor about the possibility of SIBO as a cause of too much gas.

Learn more.

6. Chronic digestive infections.

Recurrent or persistent infections can lead to constant diarrhea. The most common persistent infections that can cause diarrhea or loose stool (reference):

  • Closteroides difficile.
  • Aeromonas.
  • Giardia.
  • Amebae.
  • Campylobacter.
  • Cryptosporidium.
  • Cyclospora.
  • Whipple’s disease.

This form of diarrhea is usually severe watery and constant diarrhea for years. In addition, it may lead to complications such as malabsorption and weight loss.

Chronic infectious diarrhea is more common in people with weak immune systems. Examples are patients receiving chemotherapy, immunosuppressive medications, and people with HIV.

Your doctor usually needs to do a stool culture or take an aspirate from the small intestine or the colon to detect the causative organism.

7. Bile acid diarrhea.

Bile acid diarrhea (BAD) is one of the most underrated causes of chronic diarrhea or loose stool.

Usually, your small intestine reabsorbs more than 95% of bile excreted from the liver through the gallbladder and bile duct (reference).

Excess bile acid secretion leads to Bile acid diarrhea.

It is a common condition, affecting about 1% of the population.


  • Recurrent diarrhea and consistent loose stools.
  • Extreme urgency: a sudden severe urge to poop.
  • The extreme urgency may lead to soiling accidents (stool incontinence) in some people.
  • Unlike IBS, diarrhea can occur at night (awakens you from sleep).
  • Abdominal pain and stomach gurgling after meals.
  • Bloating and flatulence.

Loose non-solid stools alone without attacks of intense diarrhea with urgency are unlikely to be due to BAD.

The treatment of bile acid diarrhea is a bile acid binder called cholestyramine (Questran). We discussed the issue of BAD and its relation to IBS-D  in-depth HERE.

8. Inflammatory bowel disease (IBD).

Inflammatory bowel disease refers to 2 significant conditions:

  • Crohn’s disease: Unexplained inflammation and ulceration at any part of your gut (from the mouth to the anus).
  • Ulcerative colitis: Unexplained inflammation and ulceration affecting the large intestine only (the colon and the rectum).

According to the CDC, about 1.8 million U.S adults (0.9%) had inflammatory bowel disease.

symptoms of IBD:

  • Chronic or recurrent loose stool or diarrhea. 
  • Abdominal pain.
  • Blood or blood and mucus coming out with or without a stool.
  • Weight loss.
  • Generalized fatigue.
  • Fever may occur.
  • Loss of appetite.

Suspect IBD if you have a prolonged history of abdominal pain, mucus, constant diarrhea, and blood in stool without apparent cause.

The main differences between Crohn’s and ulcerative colitis are summarized below.

TypeCrohn’s DiseaseUlcerative Colitis
1- SiteAny part of the GI tract (from the mouth to the anus)The colon and rectum.
2- LesionsDeeper, it can involve all the layers of the GI wall.Usually superficial (only in the innermost layer)
3-Predominant symptomCrampy abdominal painBloody diarrhea. (can be constant)
4- ComplicationsFistulas, abscess, intestinal obstructionhemorrhagic toxic megacolon.
5- Risk of colon cancerSlight increaseMarked increase

Ulcerative colitis and Crohn’s disease are major diseases that require medical care and follow-up.

Consult your doctor if you have a long history of recurrent abdominal pain, constant diarrhea with blood, and mucus in stool.

9. Medications.

Diarrhea or loose stool for long periods can result from the medications you take. Diarrhea is a documented side effect of more than 700 medications (reference).

Common medications that can cause constant  diarrhea:

  • Antibiotics: Any antibiotic can kill the beneficial bacteria inside your colon.
  • Some anti-diabetes medications: Metformin and gliptins (vildagliptin, sitagliptin, and others), can cause diarrhea and stomach gurgling.
  • Laxative overuse.
  • Stomach/GERD medications: PPIs (as omeprazole, esomeprazole, and pantoprazole) and H2 blocker inhibit stomach acid. This inhibition will allow for the overgrowth of bacteria inside the small intestine and colon, causing stomach gurgling and diarrhea.
  • Others such as chemotherapy immunosuppressive medications can also cause such conditions.

The complete list of medications causing diarrhea is HERE and HERE.

10. Others (infrequent).

  • Colorectal cancer.
  • Lymphoma.
  • Mesenteric ischemia.
  • Previous minor intestinal surgery with removal of a part of the intestine.
  • Hyperthyroidism.
  • Chronic pancreatitis.
  • Diabetes-related diarrhea.
  • Cystic fibrosis.
  • Radiation colitis.
  • Deficiency of the blood supply to the intestine {mesenteric ischemia}.
  • Rare causes include Whipple’s disease, tropical sprue, amyloidosis, hyperparathyroidism, and Addison’s disease. 
5 Causes of Yellow Stool with GERD (Doctor Explains).

12-04-2022 · Speeding up stool passage will not leave enough time to acquire its normal brown color. The Possible common causes of yellow or pale stools with IBS are: 1. Yellow foods and food additives. Consuming too many yellow foods can turn the stool color into light brown or yellow without having diarrhea. Common examples include: Carrots. Sweet ...


GERD is the disease of the esophagus. It often doesn’t affect stool color. However, lighter (yellow) or darker colored stool may coexist with GERD due to medications, food, changes in bowel habits, or bleeding.

Yellow stool with GERD (acid reflux) is common. However, they aren’t related to GERD in most cases. But rather to dietary factors or the presence of diarrhea.

The table below summarizes the possible causes of yellow stool with GERD.


1. Yellow foods.– High-fat diet.– Carrots.– Sweet potatoes.– Tumeric.

– Food dyes and yellow artificial colorings.

2. GERD medications– Antacids.– PPIs (as Omeprazole).

– H2 blockers such as Famotidine.

3. Associated Irritable bowel syndrome.– 48.8% of people with IBS have GERD.
– IBS with predominant diarrhea causes yellow stools.
4. Food intolerance.– very common and often overlooked.
– Common offending foods include milk and dairy products, fruits, honey (containing fructose), artificial sweeteners), alcohol, etc.
5. Others.Associated conditions as:– acute infectious diarrhea (acute gastroenteritis).– bile acid diarrhea.– celiac diseases.– Gilbert syndrome.

– and others.

GERD itself is defined as the reflux of gastric acid into the esophagus. The reflux leads to inflammation and erosions of the esophageal wall.

GERD itself is not known to cause yellow stools. Instead, the origin of yellow stool with GERD can be from changes in your diet, the presence of diarrhea, or the use of certain medications.

Possible mechanisms of yellow stool with GERD include:

  • More fat in your diet.
  • Yellow foods and food additives.
  • The speeding-up of food inside your intestine and colon (AKA diarrhea or loose stool). Speeding up stool passage will not leave enough time to acquire its normal brown color.

The Possible common causes of yellow or pale stools with IBS are:

1. Yellow foods and food additives.

Consuming too many yellow foods can turn the stool color into light brown or yellow without having diarrhea.

Common examples include:

  • Carrots.
  • Sweet potatoes.
  • Tumeric.
  • High-fat foods.
  • Yellow dyes in foods or drinks.

Review your recent meals for any of the above foods. The more the amount you eat, the more likely you will have a yellow stool with GERD.

Also, Yellowish foods are the most common cause of yellow stool with GERD without having diarrhea.

2. GERD Medications

PPIs and H2-blockers:

GERD medications such as Proton pump inhibitors (PPIs) and Histaminic H2-blocker decrease the secretion of gastric acid (HCL).

Long-term use of such medication with prolonged acid suppression may alter the function of your intestines and the colon (reference).

Long-term PPI may alter your bowel habit, causing constipation or diarrhea. Diarrhea, in particular, may result in yellow stool with GERD.

Examples of PPIs and H2 blockers:

  • Omeprazole.
  • Esomeprazole.
  • Pantoprazole.
  • Dexlansoprazole.
  • Famotidine.


Many of the antacids used for GERD or acid reflux are actually laxatives. As a result, they induce diarrhea and yellow stool when taken with GERD.


  • Magnesium hydroxide (milk of magnesia).
  • Calcium carbonates (Tums).
  • Gaviscon (aluminum hydroxide and magnesium trisilicate).


3. Associated Irritable bowel syndrome.

Surprisingly, many people with Acid reflux (GERD) also have IBS. About 48.8% of patients with IBS also have GERD (reference).

IBS is a functional disease that causes recurrent abdominal pain, bloating, and changes in bowel habits (diarrhea or constipation).

IBS with predominant diarrhea or mixed type may cause yellow stool with GERD.

Check for the symptoms of IBS below and consult your doctor if you think you have IBS with GERD.

Common symptoms of IBS include:

  • Recurrent abdominal pain (at least one day per week for the past three months).
  • The onset of pain is associated with either diarrhea or constipation.
  • The onset of pain is associated with a change in stool form (It becomes loose or hard).
  • Bloating.
  • Loss of appetite.
  • The pain is either relieved or exacerbated after bowel movements.

Learn more about IBS.

4. Food intolerance.

Food intolerance is widespread. Many people are intolerant to lactose, fructose, and other foods.

For example, about 65% of people are lactose intolerant when they become adults.

Food intolerance produces symptoms similar to IBS (abdominal pain, gas, bloating, and diarrhea). In addition, recurrent yellow stools with GERD may indicate food intolerance.

Common foods that cause intolerance symptoms:

  • Lactose intolerance (found in milk and dairy products.
  • Fructose intolerance (found in most fruits and honey).
  • Caffeine intolerance (in coffee and caffeinated drinks).
  • Gluten intolerance (in celiac disease and non-celiac gluten sensitivity).
  • Others such as amines (histamine), sulfite, and salicylate intolerance.


  • The symptoms start after eating the offending food.
  • Nausea.
  • Abdominal pain.
  • Gas, distension, and bloating.
  • Diarrhea and yellow stool.
  • Headache.
  • FODMAP intolerance (in foods containing fructose, lactose, green leafy vegetables, and artificial sweeteners.
  • Alcohol.
  • Heartburn.

Learn more about food intolerance HERE.

5. Other causes of yellow stool with GERD.

  • Acute gastroenteritis (stomach flu).
  • Associated bile acid diarrhea.
  • Associated celiac disease.
  • Any other causes of chronic diarrhea (learn more).
  • Gilbert syndrome (a benign genetic defect that causes mild jaundice and yellowish stool. It affects about 5% of people.
  • Recent gallbladder removal (post-cholecystectomy diarrhea).
  • Some medications such as metformin, antibiotics, etc.

When to worry about a yellow stool with GERD:

The presence of yellow stool without diarrhea in people with GERD is not a cause of concern. In most cases, it is due to dietary factors.

See a doctor only if you have:

  • Severe diarrhea for days, weeks, or months.
  • Blood in stool.
  • Jaundice (yellowish skin and eye whites).
  • Dark (tea-colored) urine.
  • Persistent vomiting.
  • Fever.
  • Chronic diarrhea or loose stool with long-term GERD medications (more than eight weeks).
The 3 Main Reasons Why Your Hiccups Hurt (And the Best ...

31-12-2021 · 4. Why do hiccups hurt my back? Hiccups can affect your back when prolonged or severe (violent). The leading cause of back pain is often the muscle spasms or strains of the intercostal muscles at the back of the diaphragm. 5. why hiccups hurt my ribs? Hiccups can hurt your intercostal muscles by causing painful muscle cramps or even muscle strain.


We still don’t know the exact purpose or benefit of hiccups. However, during hiccups, two main events occur:

  • Sudden spasmodic contractions of the muscles of inspiration (the diaphragm and the intercostal muscles).
  • The spasmodic contraction is interrupted by a sudden closure of the epiglottis preventing air from entering your trachea.

Generally, hiccups are short-living and self-limiting within seconds or minutes. Rarely, they become frequent or prolonged and may hurt you. The pain resulting from hiccups can be due to:

  • Frequent muscle spasms.
  • Muscle strain.
  • Triggering of acid reflux.

Keep reading for more details.

A. Whey do hiccups hurt?

1. Frequent Muscle spasms.

Most of the time, hiccups last for a few minutes and don’t cause harm. However, if hiccups become prolonged or very frequent, they will hurt your muscle.

The muscles involved in the hiccup reflex start to suffer as hiccups continue. Sore muscles (the diaphragm and the intercostal chest muscles) are the leading cause.

Repetitive muscle spasms of the diaphragm and the intercostal muscles lead to a build-up of the toxic metabolites inside these muscles.

Moreover, the forceful, repetitive contractions lead to invisible microscopic damage of the cells forming the muscle fibers (reference).

The most toxic metabolite that causes sore muscle during hiccups is lactic acid.

2. Muscle strain.

Muscle strain (also called pulled muscle) occurs when a muscle is overstretched or torn. Severe or forcible hiccups can result in a strain in the diaphragm or the intercostal muscles.

The hallmark of muscle strain is the continuous pain after hiccups.


  • Discomfort or pain during breathing in and out.
  • Stitching pain in the side of your chest with movement or respiration.
  • Inability to take a full breath.
  • Pain while bending or moving.

3. Acid reflux (leads to heartburn and sore throat).

Hiccups may cause burning pain in the chest and the upper stomach area. This is because hiccups trigger the reflux of your stomach contents into the chest.

Hiccups create an intense negative pressure inside the chest, which triggers the reflux of stomach acid into the chest (esophagus).

This acid reflux with hiccups is more prominent in people who already have GERD (gastroesophageal reflux disease) and hiatal hernia. However, hiccups can also trigger acid reflux in healthy people (without GERD or hiatal hernia).

B. How to treat painful hiccups?

1. Techniques to stop hiccups.

1. Breath HoldingHold your breath for ten or more seconds (or as long as you can).
2. Valsalva Maneuver– Pinch your nose closed and close your mouth.– Forcefully exhale with mouth closed.– Bear down (similar to having a bowel movement).

– Hold this exhalation/Bearing down for 10-15 seconds.

3. Coldwater.Either sipping on or gurgling with freezing water.
4. Lemon.– Bitting into a lemon.
5. Tongue Pulling.– Pull your tongue out with your fingers (stimulates the vagus nerve).
6. Pressing on eyeballs.– Close your eyes.– Make your eyeballs look downwards while closed.

– Press gently but firmly on your eyeball (over the upper eyelid).

7. Knee-chest Position.– Sit on a chair or a couch.– Either pull your knees up to the chest OR lean forward to compress your chest with your things).

– Hold this position for at least 30 seconds to one minute.

8. FISST (forced inspiratochestction and swallow tool)sing a specialized tool (FISST or hiccup-relieving apparatus).– A specialized tube with a valve is used to suck water (requires significant effort).– Then, Swallowing of the water sucked from the tube.

– Note: Sucking stimulates the (phrenic nerve), while swallowing stimulates the (vagus nerve). Both help the termination of hiccups.

The above table explains the non-pharmacological methods to stop hiccups. However, prolonged hiccups (especially if continuous for more than 48 hours) need prescription medication to control the condition. Learn More.

2. Treatment of muscle soreness.

You can use the following tips:

  • Rest.
  • Practice slow deep inspiration and expiration (to stretch the sore muscles).
  • OTC creams and gels (such as IcyHot and Aspercreme) that contain menthol or capsaicin can ease muscle soreness.
  • Also, topical analgesics may be effective.
  • Ask your doctor about an oral analgesic for muscle soreness, such as ibuprofen, if the pain is prolonged.
  • It is better to avoid cold or hot foments

C. FAQs (Frequently-Asked Questions) about painful hiccups.

1. Is it supposed to hurt every time you hiccups?

Hiccups are often short-living and self-limiting. Typically, they don’t hurt or cause pain. However, hiccups can cause pain if they become prolonged or severe. The pain is often due to soreness of the muscles responsible for the hiccups reflex.

2. Why do hiccups hurt my throat?

Hiccups hurt your throat by two mechanisms. First, by the sudden forcible closure of the epiglottis. Second, hiccups trigger acid reflux into the esophagus, which can reach your throat and cause acid reflux pain.

3. Why do hiccups hurt my stomach?

Hiccups can hurt your stomach (abdomen) when they become frequent or prolonged. Severe hiccups cause muscle pain (soreness) in the diaphragm, intercostal and abdominal muscles. Also, hiccups may exacerbate acid reflux and hiatal hernia; both conditions cause stomach pain.

4. Why do hiccups hurt my back?

Hiccups can affect your back when prolonged or severe (violent). The leading cause of back pain is often the muscle spasms or strains of the intercostal muscles at the back of the diaphragm.

5. why hiccups hurt my ribs?

Hiccups can hurt your intercostal muscles by causing painful muscle cramps or even muscle strain. For example, you will fail as your ribs are hurting you, but the muscles cause the pain.

Why Does Omeprazole Cause Stomach Pain? Gastroenterologist ...

17-08-2021 · H. pylori is a well-known stomach bug (bacteria). It infects your stomach lining. It is a frequent risk factor for gastritis, peptic ulcer disease. Some studies also linked h. pylori to GERD (chronic acid reflux). Omeprazole may cause worsening stomach pain if you take it before treatment of h. pylori.


Omeprazole causes abdominal pain in 5% of cases. Possible causes include untreated h. pylori infection and the overgrowth of intestinal bacteria. However, abdominal pain can just be an association, not a result of omeprazole intake. 

Discuss the issue with your doctor. Don’t stop omeprazole without medical advice. 

possible causes of stomach pain with omeprazole:

  • A side effect of omeprazole. 5% of patients taking omeprazole experience abdominal pain.
  • Untreated h. pylori infection. 
  • Small intestinal bacterial overgrowth (SIBO).
  • PPIs (as omeprazole) are not your fit. 
  • Stomach pain may be just an association (not a result of omeprazole treatment).

1. Omeprazole causes abdominal pain as a side effect.

Abdominal pain is a documented side effect of omeprazole. You have a 5% risk of abdominal pain if you take omeprazole.

The exact mechanism is still not fully understood. The side effects of omeprazole don’t appear to be related to a specific age, dose, or duration of treatment (reference).

Your doctor prescribes omeprazole for conditions such as gastritis, GERD (chronic acid reflux), or peptic ulcer disease. 

Often, these conditions cause abdominal pain (upper-middle stomach pain or heartburn).

During omeprazole treatment, it is not true that every abdominal pain is omeprazole-induced.

For the pain to be omeprazole-induced stomach pain, it has to:

  • Start after taking your omeprazole, or
  • Be different in character (colics or cramps instead of gnawing pain), or
  • Be different in site ( gastritis or peptic ulcer pain is often in the upper-middle part). A change in the location of pain after omeprazole intake may indicate omeprazole-induced stomach pain.
  • Change its intensity after omeprazole (worsening of the same pain after taking omeprazole).

Your pain has to match one of the above criteria before assuming it is due to omeprazole.

2. Untreated h. pylori infection.

H. pylori is a well-known stomach bug (bacteria). It infects your stomach lining. 

It is a frequent risk factor for gastritis, peptic ulcer disease. Some studies also linked h. pylori to GERD (chronic acid reflux).

Omeprazole may cause worsening stomach pain if you take it before treatment of h. pylori. 

Some studies found that inhibiting stomach acid will allow h. pylori to flare up (reference).

The flare-up of the h. pylori infection will worsen gastritis in the long term and causes more stomach pain.

However, this assumption is still controversial. Other studies found that PPIs (as omeprazole) may result in more acid suppression in h. pylori-infected patients (reference).

Discuss the issue with your doctor if you haven’t been tested for h. pylori.

Treatment of h. pylroi may stop omeprazole from causing abdominal pain. 

3. Small Intestinal Bacterial Overgrowth (SIBO).

Your stomach acid is not pure evil. It is here for a reason.

The main function of your stomach acid is to break down food (especially protein) to prepare it for absorption.

It has another vital function. It kills bacteria and harmful pathogens. Also, your stomach acid prevents the overgrowth of intestinal microorganisms. 

By keeping them under control, stomach acid actually protects you from the harmful effects of the overgrowth of your intestinal bacteria (reference).

PPIs (as omeprazole) can cause a condition called SIBO (reference). The risk of SIBO increases with the long-term use of omeprazole. 

SIBO can be the reason why omeprazole leads to abdominal pain.

This relation between PPI and SIBO is not fully understood nor confirmed. Discuss the issue with your doctor. Don’t stop omeprazole without permission from your doctor. 

Symptoms of SIBO:

  • Stomach pain or cramps (after taking omeprazole).
  • Nausea, loss of appetite.
  • Diarrhea.
  • Bloating.
  • A feeling of fullness after eating (indigestion).
  • Weight loss.

Learn More about SIBO.

4. PPIs (as omeprazole) are not your fit.

PPIs (as omeprazole) are one of the most widely prescribed and consumed medications. It is also available as an OTC in the USA and many other countries.

Presence or persistence of stomach pain while taking omeprazole doesn’t mean that the cause is always omeprazole.

It may be a sign that omeprazole is not effective for your condition. Also, it may indicate other diseases or conditions that resemble gastritis and GERD.

Omeprazole failure to control your abdominal pain may indicate alternative diagnosis such as:

  • Functional dyspepsia.
  • Weakly acidic and biliary reflux.
  • H. Pylori infection.
  • Psychological conditions (anxiety, depression, and others) that may present with stomach pain not responding to omeprazole.
  • Functional abdominal pain.


Also, Non-compliance, incorrect dosing, and improper timing of omeprazole lead to its failure. Ineffective omeprazole leads to the persistence of your abdominal pain. 

Associated is abdominal pain with omeprazole is not always a causal relationship. Work with your doctor to assess the pain type and cause.

Don’t stop omeprazole without consulting your doctor. This may lead to more harmful effects than abdominal pain. 

Colon Cancer in Young Women: Sings, Risk Factors ...

23-10-2021 · Moreover, the signs of colon cancer in young women can be vague and non-specific. For example, constipation and diarrhea are the most common symptoms of colorectal cancer. However, in younger women, doctors attribute them to various conditions such as irritable bowel syndrome. Learn more: IBS vs. colon cancer. 1 .


Colon cancer is the third most common cancer in women and men in the united states (reference).

Young women can get coloretcal cancer, but the incidence is very low. Over 90% of the new colon cancer cases are above the age of 50.

The incidence of colon cancer in young women is very low. However, here are some statistics of colon cancer:

  • Your overall lifetime risk of getting colon cancer is about 4% for women and 4.3 for men.
  • In 2021, the American cancer society estimates are about 104K cases of colon cancer and 45K cases of retcal cancer.
  • The rate of new cases has been dropping since the mid-eighties in OLDER people due to screening programs and improvement in lifestyle habits.
  • Unfortunately, The rate is increasing in younger people (including young women).
  • The overall risk of colon or retcal cancer is very low, below the age of forty.
  • The number of cases between 15-35 years ranges from 1.3 to 3.6 cases per 100,000. This number jumps to about 88.5 cases per 100,000 above the age of 60.

The image below is from Cancer.gov, illustrating the lower risk of colon cancer in young women and men.

Risk factors of colon cancer in young women

The risk factors in more youthful women include:

  • Family history of colon or retcal cancer (a significant risk factor of coloretcal cancer in young women.
  • Obesity.
  • Eating red and processed meat.
  • Diabetes Mellitus in young age.
  • alochol.
  • Tobacco smoking.
  • Physical inactivity.

Signs & symptoms of colon cancer in young women.

Unfortunately, coloretcal cancer may not have any symptoms or signs in the early stages. Moreover, the signs of colon cancer in young women can be vague and non-specific.

For example, constipation and diarrhea are the most common symptoms of coloretcal cancer. However, in younger women, doctors attribute them to various conditions such as irritable bowel syndrome.

Learn more: IBS vs. colon cancer.

1 . Constipation or Diarrhea are the most common symptoms.

Unexplained chronic or intermittent changes in bowel habits such as constipation or diarrhea are the commonest signs of colon cancer.

However, not every diarrhea or constipation is due to colon cancer, especially if you’re a young woman. Persistent or unexplained diarrhea for long periods is an indication to see your doctor.

The most common cause of recurrent abdominal pain and bowel changes in young women are benign gut conditions such as IBS and food intolerances.

So, don’t jump to false conclusions and anxiety because of your diarrhea. Instead, ask your doctor about the most suitable way to exclude dangerous causes such as colon cancer.

Studies estimate that over 75% of patients with coloretcal cancer suffer from bowel changes (reference).

2. Blood in the stool.

About half (50%) of the cases of coloretcal cancer pass blood with stool (reference). However, the blood in the stool can be minute and unnoticeable.

In other cases, it can be seen as:

  • Black tarry stool.
  • Black spots in stool.
  • Red blood in the stool.

As a young woman, you should notice your poop color changes. Call your doctor if you see any evidence of blood in the stool.

3. A sense of mass inside the retcum

In the sigmoid colon cancer and cancers of the retcum, you may feel a mass blocking the retcum. In advanced stages, the mass can be felt in the lower left abdomen.

The condition is also common; about 25% of people living with coloretcal cancer have a sensation of a mass blocking the retcum (reference).

4. Anemia: Fatigue, shortness of breath, dizziness, and fast heartbeats.

The colon cancer mass often ulcerates and bleeds. You can notice bleeding as black or red color in the stool.

However, in many cases, the blood in the stool is not noticeable. Minor bleeding for extended periods will lead to anemia.

Unexplained anemia can be a sign of colon cancer in young women. Common symptoms and signs of anemia include:

  • Easy fatigue.
  • Shortness of breath on exertion.
  • Fast heartbeats.
  • Dizziness.
  • Lack of concentration.
  • Pale lips and hands.

5. Abdominal pain.

Unfortunately, colon cancer is often non-painful in its early stages. In addition, other symptoms and signs occur more frequently with colon cancer than abdominal pain.

Isolated abdominal pain is present in only 3.8% of the cases of colon cancer. However, it is always a late sign and associated with other more significant symptoms such as blood in stool and changes in bowel habits.

6. Weight loss.

Weight loss without trying is a red flag that is something is happening. Many cancer (including colon cancer) can manifest with unintentional weight loss in young women.

Consult your doctor if you lose more than 5% of your body weight in less than six months without trying.

7. Other signs of colon cancer in young females.

Other less frequent signs of colon cancer in young females include:

  • Nausea.
  • Loss of appetite.
  • Nighttime abdominal pain.
  • Unexplained fever.
  • Metastatic colon cancer can present with various symptoms such as liver pain, bone pain, loss of consciousness, and others.
  • Sings of complicated coloretcal cancer include intestinal obstruction (severe abdominal distention, constipation, and vomiting), Infection, or fistula formation.
How Long Nexium Takes to Heal GERD, Ulcers, Gastritis, and ...

14-08-2021 · 4 weeks (uncomplicated). 8 weeks (complicated). 7. Chronic gastritis: 2 weeks – up to 6 months or longer according to the severity: 8. Laryngopharyngeal reflux (LPR). 6 months (controversial role). (*) References to different periods are mentioned below in this article, each under its section.

  • GERD: Nexium takes around 8 weeks on average to heal GERD-related esophagitis.
  • Uncomplicated H. pylori-induced ulcers: Nexium may take 2-4 weeks to heal small uncomplicated h. pylori-induced ulcers.
  • For complicated, h. pylori-indued ulcers (with bleeding or perforation), Nexium takes 12 weeks or more to heal such ulcers.
  • For NSAID-induced ulcers: Nexium takes 4-8 weeks to heal the ulcers.
  • Chronic gastritis and laryngopharyngeal reflux take up to 6 months to heal.

MORE: Why you Should Take Pantoprazole First Thing in the Morning: Gastroenterologist Explains.

The below table summarizes how long Nexium takes to heal different conditions:

DiseaseAverage time Nexium (esomeprazole) takes to heal: (*)
1. GERD-related esophagitis.6-8 weeks.
2. Barret’s esophagus.6 months, or longer.
3. Peptic ulcers: h. pylori-related, uncomplicated, or small2 weeks.
4. Peptic ulcers: h. pylori-related, complicated (bleeding or perforation), or large in size4-12 weeks
5. NSAID-related ulcers.4-8 weeks
6. Non-h. pylori, Non-NSAID ulcers.4 weeks (uncomplicated).
8 weeks (complicated).
7. Chronic gastritis2 weeks – up to 6 months or longer according to the severity
8. Laryngopharyngeal reflux (LPR).6 months (controversial role).

(*) References to different periods are mentioned below in this article, each under its section.

1- GERD (Erosive esophagitis, Barret’s esophagus).

Nexium (Esomeprazole) takes about 8 weeks to heal GERD-related esophagitis. Studies show that up to 86% of GERD patients heal after the 8-week course of Nexium and other PPIs.

However, Your doctor may extend the duration of Nexium for up to 6 months or more. The aim is to maintain the healing of erosive esophagitis and prevent its recurrence.

If you remain symptom-free, your doctor will withdraw Nexium gradually.

 Barret’s esophagus VS erosive esophagitis.

  • Erosive esophagitis is the damage to the mucus membrane lining of the esophagus due to acid reflux (GERD).
  • Barret’s Esophagus: is abnormal healing of your esophageal mucus membrane after its damage. The healed mucus membrane becomes lined with a different cell type. Barret’s esophagus carries a high risk of malignant transformation to cancer esophagus (reference). 

In severe causes of Erosive esophagitis and barret’s esophagus, your doctor may prescribe Nexium for longer than 6 months. Nexium is effective in decreasing the risk of malignant transformation of the barret’s esophagus.

Interesting Insights from the research:

  • More than two-thirds of patients with non-erosive esophagitis have a recurrence of symptoms as heartburn (reference).
  • No significant differences in Nexium and other PPIs regarding the healing rates (reference).
  • Evidence supports the continuation of PPIs (as Nexium) indefinitely in the cases of severe reflux esophagitis and barret’s esophagus. Continued Nexium therapy may prevent cancer esophagus (reference).

However, Using Nexium long-term has some hazards and side effects. Don’t Use Nexium for extended periods without medical permission. 

2- Peptic ulcer disease.

A. H. Pylori-related ulcers:

  • Small uncomplicated ulcer, the standard 14-day course of Nexium 20 mg twice may be sufficient to heal the ulcer. However, your doctor may decide to continue Nexium if you have persistent or recurrent symptoms.
  • Eradication of H. pylori (with 7-14 days of antibiotics) is vital for Nexium to heal peptic ulcers. 
  • For large or complicated (bleeding) ulcers: your doctor will prescribe initial intravenous PPIs such as Nexium.
  • Then, a high dose of Nexium is given for 4 weeks to promote the healing of the ulcer. 
  • Nexium may require up to 12 weeks (3 months) to heal H. pylori-related ulcers (reference).

B. anallgesic or NSAID-induced ulcers.

Nexium takes about four to eight weeks of treatment to heal NSAID-induced ulcers. If you need to remain on NSAID (as aspirin), your doctor may prescribe low-dose PPI (as Nexium 20 mg) for extended periods. 

The 4-8 week course of Nexium is often sufficient to heal NSAID-induced ulcers. 

Non-h. pylori, Non-NSAID ulcers.

According to uptodate.com expert suggestion, for Nexium to heal such ulcers, it may take up to:

  • 4 weeks for uncomplicated duodenal ulcers.
  • 8 weeks for uncomplicated stomach ulcers.

Some ulcers (gastric and duodenal) are refractory to the standard 8-12 weeks treatment. Your doctor may prescribe Nexium for another additional 12 weeks. Also, He may prescribe Nexium twice a day, or add a bedtime H2 blocker (reference).

3- Chronic gastritis.

Chronic gastritis occurs due to a variety of causes. However, the most common are H. pylori-related gastritis and NSAID-induced gastritis.

The duration required for Nexium to heal gastritis varies according to the cause and the severity. 

Your doctor may prescribe Nexium (or other PPIs) for Two weeks up to 6 months or indefinitely according to the severity and the cause. 

Treatment of the cause (such as stopping anallgesics and H. pylori treatment) is needed for Nexium to heal gastritis. 

Learn more about gastritis and gastropathy.

4- Laryngopharyngeal reflux (LPR).

LPR is the reflux of stomach contents (acid and digestive enzymes) into your throat (reference).

LPR usually accompanies GERD (acid reflux). No sufficient data in research regarding the duration needed for PPIs (as Nexium). 

A 6-month course of Nexium (or any other PPI) is recommended by the American Academy of Otolaryngology-Head and Neck Surgery. The 6-month period appears to be the average duration needed for Nexium to heal LPR.

Nexium may be less effective if LPR is not accompanied by GERD symptoms.

The AGA (Americal Gastroenterological Association) recommends AGAINST the use of PPIs (as Nexium) for isolated LPR without GERD (reference).

This diversity in recommendation reflects the lack of strong scientific evidence regarding the use of PPIs for LPR. Discuss the issue with your doctor. 

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